But many agree that the brain has varied pathways to protection, including storing memories in ways that may not be completely remembered at all times. And that’s worth remembering.Experts are split about repressed memories and trauma versus other explanations. Regular memory failures can often be deliberately and methodically overcome, while changes in memory over time are often due to people maintaining a positive sense of self. So for most of us, forgetting things is not just normal – but desirable. The reality of remembering everything would be an overwhelming experience. One of those “super mnemonists” has described the ability as “a curse plays over and over in my mind”. They can remember what the weather was like on March 6 2016, for example, or what they had for lunch on the September 15 2004. That said, there are rare cases of people who claim to have “super memories”. It simply is not feasible to remember everything we experience. Most people’s memories fail them regularly, and this is because our minds have a limited ability to process all the information in our environment. So if I feel I love you more than yesterday, it is ultimately beneficial to feeling positive about myself – even if it is not objectively true. Instead, they found that long-term couples have a commitment to each other that is important for their own personal well being. How sleep makes the brain forget things – new research on miceĪnother interesting example of this kind of beneficial “self-editing” is where long-term couples will say to their other half: “I love you more today than yesterday.” When psychologists examined this concept, they found it not to be entirely true. I have subconsciously edited out the negative aspect to create a more positive recollection. Shutterstock/ROMSVETNIKĪnd if I remember a totally happy holiday and repress the negative incident at the airport, this actually helps me feel better about myself and my experience. (Apparently one of former US president Bill Clinton’s strengths as a charismatic politician was that he always remembered people’s names – but this certainly wouldn’t have come without a level of deliberate concentration.) Or, if I want to remember someone’s name, I ensure that on meeting them, I make an extra effort to register their face, say their name aloud, and perhaps try to associate it with someone else of the same name. It’s a simple but effective solution which requires practice (and remembering to enact): always put your keys in the same place. If I am constantly forgetting where I put my keys, I develop a routine to deal with the situation. And while memory lapses can be frustrating, there are ways around them, which can sometimes be beneficial to that sense of self. So what is memory for, and why is forgetfulness such a prevalent experience? Memory serves to give us a record of our lives, to situate us in the present and to plan for the future. Or perhaps the memory has been altered in some regard along the way, when you’re convinced something happened on a Thursday, yet all the facts point to it being a Tuesday. In other cases there is clearly a memory there, but it’s just not retrievable – such as when a name you know is on the tip of your tongue. For example, sometimes it’s clear that we simply haven’t set a proper memory down in our mind in the first place, like when we forget why we went upstairs. The various types of forgetting involve different issues.
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ctDNA reflects tumor genome and may also reflect disease burden. Apoptosis and necrosis due to rapid cell growth and increased cell turnover contribute to release of ctDNA in circulation of patients with cancer even without disseminated disease. Currently there are no useful biomarkers for surveillance or diagnosis of recurrent HNSCC.Ĭirculating tumor DNA (ctDNA) is tumor-derived fragmented DNA circulating freely in the bloodstream. The overall 5-year survival is approximately 50 % due to often advanced clinical stage at diagnosis, high rate of treatment resistance, and high incidence of second cancers. Head and neck squamous cell carcinoma (HNSCC) stands as the sixth most common cancer worldwide. The investigators hypothesize that LB could assist or replace PET/CT in response monitoring and detection of recurrence after RT/CRT. ctDNA and digital droplet PCR will be quantified and compared to MTV in simultaneously acquired PET-CT. Before onset and 3 months from RT/CRT, LB is obtained for next-generation DNA sequencing using a commercial platform. This prospective study includes 30 patients with stage III/IV HNSCC. Third (iii), genetic landscape in LB and fresh tumor samples will be evaluated to detect resistance genes and targets for immunotherapy and surveillance post-treatment. Another objective is (ii) to determine sensitivity of LB compared to PET/CT in detecting residual tumor 3 months after completion of RT/CRT. The objective is (i) to investigate whether MTV detected with PET-CT correlates to the pattern and amount of genetic alterations in ctDNA of patients with HNSCC referred to radio- (chemo)therapy (RT/CRT). High metabolically active tumor volume (MTV) is associated with treatment resistance and shows independent prognostic significance. Increased metabolic activity measured in positron emission tomography-computed tomography (PET-CT) is currently the most sensitive technique to detect residual cancer or progression of HNSCC after curative treatment. LB has potential to assist in early diagnosis of recurrence and progression, and prediction of response to targeted therapeutic agents. ctDNA reflects tumor genome and disease burden and is termed 'liquid biopsy' (LB) when collected through venous bloodstream. About 75 % of patients with localized HNSCC are expected to show circulating tumor DNA (ctDNA) pre-treatment. Overall survival of patients with head and neck squamous cell carcinoma (HNSCC) remains unsatisfactory due to often advanced clinical stage at diagnosis and high rate of recurrence and second primaries. Why Should I Register and Submit Results?. Simplify, automate, and optimize the management and compliance of your cloud resourcesīuild, manage, and monitor all Azure products in a single, unified console Quickly spin up app infrastructure environments with project-based templates Streamline development with secure, ready-to-code workstations in the cloud Optimize app performance with high-scale load testing Get the SDKs and command-line tools you needīuild, test, release, and monitor your mobile and desktop appsįull observability into your applications, infrastructure, and network World’s leading developer platform, seamlessly integrated with AzureĬomprehensive set of resources to create, deploy, and manage appsĪ powerful, low-code platform for building apps quickly Powerful and flexible environment to develop apps in the cloudĪ powerful, lightweight code editor for cloud development Modernize Cassandra data clusters with a managed instance in the cloudĭeploy applications to the cloud with enterprise-ready, fully managed community MariaDBīuild, manage, and continuously deliver cloud applications-using any platform or language Modernize SQL Server applications with a managed, always-up-to-date SQL instance in the cloudĪccelerate apps with high-throughput, low-latency data cachingĪzure Managed Instance for Apache Cassandra Support rapid growth and innovate faster with secure, enterprise-grade, and fully managed database servicesīuild apps that scale with managed and intelligent SQL database in the cloudįully managed, intelligent, and scalable PostgreSQL Seamlessly manage Kubernetes clusters at scaleĪzure Kubernetes Service Edge Essentials is an on-premises Kubernetes implementation of Azure Kubernetes Service (AKS) that automates running containerized applications at scale. Launch containers with hypervisor isolationĭeploy and operate always-on, scalable, distributed appsīuild, store, secure, and replicate container images and artifacts Run containerized web apps on Windows and Linux Provision unused compute capacity at deep discounts to run interruptible workloadsīuild and deploy modern apps and microservices using serverless containersĭevelop and manage your containerized applications faster with integrated toolsĭeploy and scale containers on managed Red Hat OpenShift Migrate SQL Server workloads to the cloud at lower total cost of ownership (TCO) Manage and scale up to thousands of Linux and Windows VMsīuild and deploy Spring Boot applications with a fully managed service from Microsoft and VMwareĪ dedicated physical server to host your Azure VMs for Windows and LinuxĬloud-scale job scheduling and compute management Remove data silos and deliver business insights from massive datasetsĪccess cloud compute capacity and scale on demand-and only pay for the resources you use Secure, develop, and operate infrastructure, apps, and Azure services anywhere Jump in and explore a diverse selection of today's quantum hardware, software, and solutions Quickly create powerful cloud apps for web and mobileĮverything you need to build and operate a live game on one platformĮxecute event-driven serverless code functions with an end-to-end development experience Migrate, modernize, and innovate on the modern SQL family of cloud databasesīuild or modernize scalable, high-performance appsĭeploy and scale containers on managed KubernetesĪdd cognitive capabilities to apps with APIs and AI services Provision Windows and Linux VMs in secondsĮnable a secure, remote desktop experience from anywhere Explore some of the most popular Azure products However, Springer Pits are smart, easily trained and affectionate. Plus, they tend to inherit distinctive Pit Bull qualities, such as the face and ears. They’re high energy dogs and require a lot of physical activity to dissipate all that energy. Springer Pits are muscular and compact with strong legs and really strong jaws. Springer Pit coats can come in a variety of colors such as black, white, blue, brindle or a combination. They are medium dogs with short to medium-length hair. Parents: Springer Spaniel x Pit Bull mix via Instagram: Springer Pit is a mix of an English Springer Spaniel and an American Pitbull Terrier. They’re also likely to inherit the independent nature and the stubbornness from the Pit Bull Terrier side. This cross between two powerful canine breeds - both of which have strong natural guarding instincts – is loyal and protective. Some of the Pyrenees Pits may have single coats, while others may have double coats. These dogs can have sturdy heads, a solid neck and broad, deep muzzles. That said, Pyrenees Pits grow to be 21 to 27 inches high and weigh from 60 to 95 lbs. The mix is not something you see every day. However, the Pyrenees Pit is often smaller than the Great Pyrenees, while inheriting the facial traits of the Pit Bull parent. Parents: Great Pyrenees x Pit Bull mix via Instagram: hybrid of the Great Pyrenees and Pit Bull can take after either parent breeds. Overall, they tend to be sweet dogs that are obedient, though they can be wary of strangers. Regarding personality or temperament, there can be a lot of variation as both the Chow and an American Pitbull Terrier have diverse temperaments. However, they can live an astounding 10 – 15 years! A Pit Chow can grow to be 17 to 21 inches in height and weigh anywhere from 30 to 70 lbs. Pit Chows, the mix of these two breeds, have a range of appearances as they take after both parents. Meanwhile, the Chows are ancient Chinese dogs bred for various work. Pit Bulls were involved in bull and bear baiting, along with dog fighting before those blood sports were banned. Parents: Chow Chow x Pit Bull mix via Instagram: Chows are born from an American Pitbull Terrier and a Chow Chow. If we’ve missed a mix that deserves to be on this list, let us know in the comments section below! 1. This list could be shorter, but we have narrowed it down to our 31 favorite Pit hybrids. We list a few of the most interesting Pit bull mixes here. But proper socialization, obedience training, and showering them with love, can transform them into any other loving family companion. And yes, they do top the list for dog bite fatalities. With their strong jaws and strong necks, a Pit bull’s bite can do a lot of damage. However, this is more likely due to poor training and negligence by the owners rather than the dog itself. In fact, they take the number 1 spot for most frequent dog bites. There is some merit to this, as Pit Bulls are often on the lists of most dangerous dogs. But here’s the elephant in the room: there’s a general perception that these dogs are highly aggressive and prone to attacking strangers (or other animals). Most owners consider their Pit Bulls to be intelligent and friendly, though they can certainly go on their stubborn streaks. All of them thought they were lap dogs and they were never aggressive to anyone – not even other dogs. I’ve had many many pitbulls, and they are THE SWEETEST. They will be compact and dense, with a powerful yet effortless gait. More often than not, they will have cropped ears and can come in a variety of terrier colors. With that said, Pitbulls are typically medium-sized dogs with muscular bodies. Rather, it refers to a type of dog ( read here) and can be derived from 4 distinct pedigree breeds: an American Pit Bull Terrier, American Staffordshire Terrier, Staffordshire Bull Terrier and the American Bulldog. The word “pit bull” doesn’t refer to one dog breed. RECOMMENDED: 21 Interesting Mixed Dogs What’s a Pit Bull? But don’t worry – here are our 31 favorite Pit Bull mixes. There are plenty of options to choose from. For this reason, hybrids that contain part Pit Bull are also widespread. There are so many Pit Bulls in the world today, especially in America. If properly trained and socialized, there’s no reason why they wouldn’t be as loving as any other dog. Whatever the myths and myth-makers may say, Pit Bulls are friendly and outgoing dogs that deserve a loving home. On the contrary, this super-energetic and affectionate dog breed has earned a well-deserved reputation for its courage. It’s no secret, Pit Bulls receive a lot of bad press for being “dangerous dogs.” However, there are so many Pit Bull myths which can be debunked. Easy ways to make your fresh fruit and veg last longer so there's less waste and it'll save you money.Much-needed boost for Rishi Sunak as he faces threat of triple by-election disaster this week - with Tories left £10m by Sainsbury's tycoon in biggest ever donation.Jane Birkin dies aged 76 after long battle with cancer: Singer, actress and style-icon who had on-off relationship with Serge Gainsbourg and lent her name to famous Hermes Birkin designer handbag is found at home in France by her carer. Plans to shut train station ticket offices could lead to 2,000 job losses, documents reveal - as RMT boss Mick Lynch says he has not met government minister since January as rail unions prepare for strike action this week.Union reps would get paid time off to campaign on 'equalities' issues including trans rights, under Labour plans.Singer Ronan Keating's older brother, who is in his 50s, is killed in car crash while travelling with his wife to watch their son play football.Ukraine stages its most intense drone attack on Putin's naval port Sevastopol in annexed Crimea.
My aim with this Yoga Challenge is to become more attune with myself and the world around me – to become overall more mindful in my day-to-day life. Yoga in the past has helped to be be more mindful with my food choices by helping me reduce my overall stress level and thus not give into stress or binge eating – but that is another story altogether. I have been itching to do a 30 day yoga challenge and stumbled across Esther Ekhart’s September Yoga Challenge. This is exactly where September goals come in. None of the latter is happening when I am going through the day mindlessly snacking. Which kind of takes the joy out of eating altogether doesn’t it? Food is meant to be nourishing and bring us joy. Especially since that when meal time does roll around I am often no longer hungry. Not that this is the end of the world but I would much prefer to sit down and enjoy my meals instead of mindlessly snacking throughout the day. As in you are working on a paper or doing something around the house and all of the sudden your homemade jar of trail mix has somehow disappeared and that half that bar of dark chocolate suddenly seems to be missing. Over the past couple weeks I’ve noticed some of my clothing fitting a little more snug than usual and have also noticed myself slipping into old habits of mindless snacking. The darker shades of the foundation sold out immediately upon its initial launch. Fenty Beauty’s cosmetics line launched with 40 shades, with 10 additional shades added earlier this year. It wasn’t until singer Rihanna launched her signature makeup collection Fenty Beauty Septemin SEPHORA, that beauty brands final began paying attention to black women. This is not surprising to see as, since the beginnings of America’s beauty industry, black women have been consistently ignored. A 2017 Color Cosmetics study from Mintel reports that black women have a lower usage of facial makeup than white women (Mintel, 2017). While sales of makeup have proven to be lucrative for women of all races, there is a serious sales gap when it comes to shade specific products such as foundation. The purpose of this thesis study is to take a mixed methods and black feminist approach (while honoring my role as a former beauty editor and black woman) to find out how black woman are represented within the beauty advertisements of women’s fashion magazines.Īccording to research firm Mintel, sales for beauty products in the United States have an overall estimated net worth of $445 billion (Mintel, 2017). And, if you asked a publicist why, they’d just give a flippant response like, “Oh, well, we just send over the products that we think will work best for ESSENCE and its readers.” Of course, ESSENCE’s top audience consists of black women, but how could a person conclude, based on one’s skin color, what beauty products a person may or may not use? Is this just the way some beauty publicists were thinking, or is it part of a bigger issue within America’s beauty industry? If sending over beauty products to magazines is part of the larger marketing plan for brands to get noticed, then why were editors at traditionally black publications such as ESSENCE given the shorter end of the product pool stick? Of course, it was great to see all the newest launches before they hit the market, but it was often quite disturbing when chatting with beauty editors from other publications such as Cosmopolitan and Vogue about the products and finding out that beauty brands weren’t sending over even half of the items that others got. Part of my daily job duties included organizing the mounds of beauty products that publicists would messenger over to the office in overstuffed shopping bags. Beauty can take on a totally different meaning, depending on where a person lives in the world however, as a former beauty editor working at ESSENCE magazine in New York, I would err to say that, in America, the majority of its clarification can be found in race. Popular quotes have espoused the key to beauty as lying within the beholder, while some say that it can be found within. The word “beauty” has no shortage of scholarly work that’s been conducted on its meaning, how it should look and its history. These three tests - Speedometer 2.0, JetStream 2 and Motion Mark - each analyze different aspects of your web browser. That’s why we use the suite of benchmark tests provided by BrowserBench. Testing the speed of a browser is a delicate task because the browser’s speed must be parsed out from your internet connection’s speed. How Did We Determine the Fastest Web Browsers? Each browser has its strengths and weaknesses, and you’ll see how some browsers perform better in some areas than others. We also take visual graphics rendering into account, as you’ll see in our results below, but it’s not the most significant factor. Vivaldi - Consumes a lot of RAM, but includes resource-saving features like hibernating tabs.Brave - It’s not the fastest, but it is the most secure browser on this list, with built-in privacy and security features that don’t burden its great performance.Opera - The third-fastest browser, but its speed is hampered by its abundance of features.Microsoft Edge - A close runner-up to Chrome, and Chrome’s equal in practice.Chrome - The overall fastest browser, and one of the most popular browsers.However, we don’t overlook the more advanced, resource-heavy applications, either. Handling standard web applications is the most important criterion because that’s what the majority of web browsing activity consists of. When we’re assessing the speed of a browser, we look at its ability to execute web applications and render visuals. Review Visit Vivaldi What Makes the Fastest Browser & Which Browser Is the Fastest? For example, one that’s fast with standard web applications might be slower when rendering visuals, or vice versa. Some browsers are faster when dealing with certain kinds of web applications than others.Speed can come at the cost of other important factors in a browser, such as security and features.Google Chrome and Microsoft Edge were nearly tied for first place, but we think Chrome is the faster web browser.We tested a total of 10 web browsers and picked what we believe are the five fastest internet browsers on the web. That’s why we tested the desktop versions of all the major internet browsers and compiled their results in this browser speed overview. Browser speed also often changes with each update, so there’s a good chance any information you might find about a browser’s speed will be outdated. The performance of your browser is difficult to separate from the speed of your internet connection, so you might find yourself a little lost when looking for the fastest browser on the web. MP4 Repair: How to Fix Corrupted Video Files in 2019.Best Choice Stellar Phoenix Data Recovery.How to Create a Strong Password in 2023: Secure Password Generator & 6 Tips for Strong Passwords.How to Securely Store Passwords in 2023: Best Secure Password Storage.Best Password Manager for Small Business.How to Access the Deep Web and the Dark Net. Online Storage or Online Backup: What's The Difference?.Time Machine vs Arq vs Duplicati vs Cloudberry Backup. The flavour bomb is finished with sesame oil, soy sauce, slivered scallions, cilantro, sliced fresh chilli pepper, and peanuts. Some of those Taiwanese-influenced snacks and punchy flavours can be found here, such as the Spicy Wonton in XO Broth ($25/6 pieces) which dresses handmade pork and shrimp wontons with bomb chilli crisp, scallion, cilantro, and Betty's XO sauce. until close every Thursday to Monday.Ĭhia had worked at Sofia and Speaskeasy21, but is best known for the handmade dumpling and sauce pop-up, Eats by Betty, she operated during the pandemic. Here, a gluten-free tempura batter shields the delicate whole perch sourced from Affinity Fish that's dressed with a braised kale salad with salsa verde.īetty Chia oversees the evening menu that starts at 7 p.m. Made to 0rder, it's become the menu signature that's found a harmonious balance between the sweet vegetables, supple melted cheese, and flavourful beef sandwiched by a semolina-spiked focaccia bun (semolina gives the bread a slight crunch).Ī showstopper, Wilkes' Butterflied Whole Perch ($33) is a delight for all senses. The former is topped with provolone then silky sweet roasted peppers and onions that are refreshed in the same beef drippings that's served alongside the handheld wonder. The Cartl Beef Sando ($16) stuffs juicy and tender braised beef in homemade focaccia which has been adapted from a 250-year-old recipe that was passed down to Wilkes. This vegetarian-friendly option is hearty and delicious, with fresh springy pasta noodles that are coated in a voluptuous sauce made of butter and a shower of grated pecorino. Known for his pastas, Wilkes' handmade Tagliolini ($18) features Ontario mushrooms (meaty and glorious wild chanterelles on our visit). every Wednesdays to Monday, Cody Wilkes, who worked at Mattachioni and Gusto 501, runs his Pasta Cartl menu that features an assortment of homemade bread, pasta and chicchetti that incorporate local, seasonal, and ethically sourced ingredients. Just outside on Dunn Avenue, Chick shares plans for a veranda-covered patio that seats 32.Ĭhick has recruited two chefs in residence who operate the daytime and nighttime food programs independently.ĭuring the day until 6 p.m. This is also where you'll find a refrigerator case filled with homemade pantry goods that can be purchased for takeaway. The south end is clean and understated, with seats that flank Simpl Thing's open kitchen. Here, shelves are lined with glass pieces in a variety of hues that were inspired by Chick's mother's cabinet, and the room is furnished with vintage pieces including steel-coated ergonomic stools from the '70s that were sourced from auction. It’s based on the healthy meals and snacks recipes in the cookbook. The Morning Meltdown 100 Nutrition Plan is SIMPLE (which is key!). THIS IS THE SECRET TO LOSING WEIGHT! (As much as people like to complicate it, it’s really as simple as this. The ultimate goal is to eat nutrient dense single ingredient foods (AKA whole food nutrition) AND end the day at a calorie deficit. In short, it all boils down to what you eat and how much of it you eat. Here’s one blog post where we cover this topic- You Can’t Out Exercise a Bad Diet We’ve covered this concept a lot in this blog for YEARS - diet is the MOST important aspect of the weight loss process. To lose weight, you need to follow the Morning Meltdown 100 nutrition plan. Sure, you’ll burn calories, but the workouts are mostly designed to improve your cardiovascular system and tone your muscles. If you’re going for weight loss, I will let you know now that the Morning Meltdown workouts are not enough. It’s really up to you-do you want a major transformation, lose those stubborn 10-15 pounds, or maintain your weight? Whatever your goal, Morning Meltdown 100 has all the tools you need to reach it.
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